Settings can be adjusted for each segment — they are responsible for the logic of ad distribution. E.g. you can set the minimal price for a fullscreen banner impression in a particular country.
The following settings are available:

Disable Ad Types — turning off any ad types;
Disable Network —  turning off ad networks by ad type;
Minimal Pricefloor — setting the minimal price floor by impression for each ad type separately;
Overriden eCPM — setting ad network eCPM for each ad type separately; influences the position in the waterfall.

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